Home GPCR & G Protein LPA Receptor LPA1 Antagonists

LPA1 Antagonists

  • LPA1
  • LPA2
  • LPA3
N° de cat. Nom du produit Informations Sélectif / Pan IC50 / Ki
S1315 Ki16425 Ki16425 is a competitive, potent and reversible antagonist to LPA1, LPA2 and LPA3 with Ki of 0.34 μM, 6.5 μM and 0.93 μM, respectively, shows no activity at LPA4, LPA5, LPA6. Pan LPA1, Ki: 0.34 μM
S2906 Ki16198 Ki16198 is the methyl ester of Ki16425, which is a LPA antagonist and inhibits LPA1- and LPA3-induced inositol phosphate production with Ki of 0.34 μM and 0.93 μM, respectively, shows weaker inhibition for LPA2, no activity at LPA4, LPA5, LPA6. Pan LPA1, Ki: 0.34 μM