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Fragment Library

Kat.-Nr.L1600

Eine einzigartige Sammlung von 1015 Fragmentverbindungen für die fragmentbasierte Arzneimittelentdeckung (FBDD).

96 well plates

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Zitiert von 3 Publikationen

Fragment Library Inhalt

Beschreibung & Vorteile

• A unique collection of 1015 Fragment compounds for Fragment-Based Drug Discovery (FBDD)
 
• FBDD has emerged as an alternative approach for high-throughput screening (HTS) in discovering drug
 
• These fragments with low molecular weight are extremely suitable for screening clinical candidates with good drug-like properties,and more and more compounds discovered by FBDD are entering the clinic
 
• FBDD can save research cost and make it easier to screen high-performance drugs
  Range Average
MolWeight 92 to 291 164.8
LogP <3.8 1.5
Num_H_Acceptors 0 to 6 2.4
Num_H_Donors 0 to 3 1
Num_RotatableBonds 0 to 8 1.5
PSA 0 to 99 8

 

Produktdetails

Formulierung 1015 compounds pre-dissolved in 10mM DMSO
Behälter 96 Deep-Well-Platte mit Aluminiumfolie versiegelt
Stabilität 12 months -20°C in DMSO
24 months -80°C in DMSO
Versand Kühlakku oder Trockeneis

Fallstudien mit Selleck Compound-Bibliotheken

Fragment Library Zusammensetzung

HTS-Anlagenpartner

  • Collaborating with Seleck: Yale University | Yale Center for Molecular Discovery
  • Collaborating with Seleck: Carbone Cancer Center | University of Wisconsin-Madison
  • Collaborating with Seleck: University of Colorado Denver | CU Denver
  • Collaborating with Seleck: Leibniz-Forschungsinstitut für Molekulare Pharmakologie: Leibniz-FMP
  • Collaborating with Seleck: UCSF_University of California San Francisco
  • Collaborating with Seleck: KU | High Throughput Screening Laboratory
  • Collaborating with Seleck: CIBIO
  • Collaborating with Seleck: Perelman school of medicine | University of Pennsylvania