Home Apoptosis -Proteases Caspase Caspase-3-selektive Inhibitors | Activators

Caspase-3-selektive Inhibitors | Activators

  • Caspase-1
  • Caspase-3
  • Caspase-4
Kat.-Nr. Produktname Informationen Selektiv / Pan IC50 / Ki
S2738 PAC-1 PAC-1 is a potent procaspase-3 activator with EC50 of 0.22 μM and the first small molecule known to directly activate procaspase-3 to caspase-3. Selective Procaspase-3, EC50: 0.22 μM
S2927 Apoptosis Activator 2 Apoptosis Activator 2 strongly induces caspase-3 activation, PARP cleavage, and DNA fragmentation which leads to the destruction of cells (Apaf-1 dependent) with IC50 of ~4 μM, inactive to HMEC, PREC, or MCF-10A cells. Selective
S7312 Z-DEVD-FMK Z-DEVD-FMK is a specific, irreversible Caspase-3 inhibitor, and also shows potent inhibition on caspase-6, caspase-7, caspase-8, and caspase-10. Selective