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HD1-selektive Inhibitors

  • HDAC1
  • HDAC2
  • HDAC3
  • HDAC4
  • HDAC5
  • HDAC6
  • HDAC7
  • HDAC8
  • HDAC9
  • HDAC10
  • HDAC11
  • HD1
  • HD2
Kat.-Nr. Produktname Informationen Selektiv / Pan IC50 / Ki
S1484 MC1568 MC1568 is a selective HDAC inhibitor for maize HD1-A with IC50 of 100 nM. It is 34-fold more selective for HD1-A than HD1-B. Selective HD1-B (Maize), IC50: 3.4 μM; HD1-A (Maize), IC50: 100 nM
S2170 Givinostat (ITF2357) Givinostat (ITF2357) is a potent HDAC inhibitor for maize HD2, HD1B and HD1A with IC50 of 10 nM, 7.5 nM and 16 nM. Phase 2. Pan HD1-B, IC50: 7.5 nM; HD1-A, IC50: 16 nM