RXR-selektive Agonists
- RAR
- RXR
| Kat.-Nr. | Produktname | Informationen | Selektiv / Pan | IC50 / Ki |
|---|---|---|---|---|
| S2098 | Bexarotene | Bexarotene is a retinoid specifically selective for retinoid X receptors, used as an oral antineoplastic agent in the treatment of cutaneous T-cell lymphoma. | Selective | |
| S1653 | Tretinoin | Tretinoin, which is a ligand for both the retinoic acid receptor (RAR) and the retinoid X receptor (RXR), can induce granulocytic differentiation and apoptosis in acute promyelocytic leukemia (APL) cells. | Pan | |
| S1276 | Adapalene | Adapalene is a dual RAR and RXR agonist, used in the treatment of acne. | Pan |
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