Home Apoptosis Bcl-2 A1 Inhibitors

A1 Inhibitors

  • Bcl-2
  • Bcl-B
  • Bcl-w
  • Bcl-xL
  • Mcl-1
  • A1
  • Bax
  • Bfl-1
Kat.-Nr. Produktname Informationen Selektiv / Pan IC50 / Ki
S1001 ABT-263 (Navitoclax) ABT-263 (Navitoclax) is a potent inhibitor of Bcl-xL, Bcl-2 and Bcl-w with Ki of ≤ 0.5 nM, ≤1 nM and ≤1 nM, but binds more weakly to Mcl-1 and A1. Phase 2. Pan A1, Ki: 354 nM