Home Metabolism P450 (e.g. CYP17) CYP17-selektive Inhibitors

CYP17-selektive Inhibitors

  • P450
  • CYP2
  • CYP3
  • CYP1
  • CYP17
Kat.-Nr. Produktname Informationen Selektiv / Pan IC50 / Ki
S1123 Abiraterone Abiraterone is a potent CYP17 inhibitor with IC50 of 2 nM. Selective CYP17, IC50: 2 nM
S2246 Abiraterone Acetate Abiraterone Acetate is an acetate salt form of Abiraterone which is a steroidal cytochrome CYP17 inhibitor with IC50 of 72 nM. Selective CYP17, IC50: 72 nM
S2803 Galeterone Galeterone is a selective CYP17 inhibitor and androgen receptor (AR) antagonist with IC50 of 300 nM and 384 nM, respectively, and is a potent inhibitor of human prostate tumor growth. Phase 2. Selective CYP17, IC50: 300 nM