Home Neuronal Signaling -GPCR & G Protein Dopamine Receptor D2 receptor-selektive Inhibitors | Agonists | Antagonists

D2 receptor-selektive Inhibitors | Agonists | Antagonists

  • D1 receptor
  • D2 receptor
  • D3 receptor
  • D5 receptor
  • DAT
  • D4 receptor
Kat.-Nr. Produktname Informationen Selektiv / Pan IC50 / Ki
S3044 Lurasidone HCl Lurasidone is an atypical antipsychotic, inhibits Dopamine D2, 5-HT2A, 5-HT7, 5-HT1A and noradrenaline α2C with IC50 of 1.68 nM, 2.03 nM, 0.495 nM, 6.75 nM and 10.8 nM, respectively. Selective D2 receptor, IC50: 1.68 nM
S3189 Ropinirole HCl Ropinirole a selective dopamine D2 receptors agonist with Ki of 29 nM. Selective D2 receptor, Ki: 29 nM
S4289 Metoclopramide HCl Metoclopramide HCl is a selective dopamine D2 receptor antagonist, used for the treatment of nausea and vomiting. Selective
S4251 Phenothiazine Phenothiazine is a dopamine-2 (D2) receptor antagonist therefore decreases the effect of dopamine in the brain. Selective
S2104 Levosulpiride Levosulpiride is a selective antagonist for D2 dopamine receptors used as an antipsychotic and prokinetic agent. Selective
S2493 Olanzapine Olanzapine is a high affinity for 5-HT2 serotonin and D2 dopamine receptor antagonist. Selective
S2460 Pramipexole Pramipexole is a partial/full D2S, D2L, D3, D4 receptor agonist with a Ki of 3.9, 2.2, 0.5 and 5.1 nM for D2S, D2L, D3, D4 receptor, respectively. Pan D2S Receptor, Ki: 3.9 nM; D2L Receptor, Ki: 2.2 nM
S2011 Pramipexole 2HCl Monohydrate Pramipexole 2HCl Monohydrate is a partial/full D2S, D2L, D3, D4, receptor agonist with a Ki of 3.9, 2.2, 0.5, 5.1 nM. Pan D2S Receptor, Ki: 3.9 nM; D2L Receptor, Ki: 2.2 nM
S1771 Chlorprothixene Chlorprothixene has strong binding affinities to dopamine and histamine receptors, such as D1, D2, D3, D5, H1, 5-HT2, 5-HT6 and 5-HT7, with Ki of 18 nM, 2.96 nM, 4.56 nM, 9 nM, 3.75 nM, 9.4 nM, 3 nM and 5.6 nM, respectively. Pan D2 receptor, Ki: 2.96 nM
S4086 Loxapine Succinate Loxapine Succinate is a D2DR and D4DR inhibitor, serotonergic receptor antagonist and also a dibenzoxazepine anti-psychotic agent. Pan D2 receptor (bovine), Ki: 26 nM; D2 receptor (Human), Ki: 24 nM; D2 receptor (human), Ki: 24 nM
S2437 Rotundine Rotundine (L-tetrahydropalmatine, L-THP) is a selective dopamine D1 receptor antagonist with IC50 of 166 nM. Pan D2 receptor, IC50: 1.47 μM