Home GPCR & G Protein -Stem Cells & Wnt Hedgehog/Smoothened Hedgehog-selektive Inhibitors

Hedgehog-selektive Inhibitors

  • Hedgehog
  • Smoothened
  • GLI
Kat.-Nr. Produktname Informationen Selektiv / Pan IC50 / Ki
S1082 Vismodegib (GDC-0449) Vismodegib (GDC-0449) is a potent, novel and specific hedgehog inhibitor with IC50 of 3 nM and also inhibits P-gp with IC50 of 3.0 μM. Selective Hedgehog, IC50: 3 nM