Home TGF-beta/Smad -Epigenetics -Cytoskeletal Signaling PKC PKCη Inhibitors

PKCη Inhibitors

  • PKCα
  • PKCβ
  • PKCγ
  • PKCδ
  • PKCε
  • PKCζ
  • PKCη
  • PKCθ
  • PKCμ
Kat.-Nr. Produktname Informationen Selektiv / Pan IC50 / Ki
S2791 Sotrastaurin Sotrastaurin is a potent and selective pan-PKC inhibitor, mostly for PKCθ with Ki of 0.22 nM; inactive to PKCζ. Phase 2. Pan PKCη, Ki: 1.8 nM
S1421 Staurosporine Staurosporine is a potent PKC inhibitor for PKCα, PKCγ and PKCη with IC50 of 2 nM, 5 nM and 4 nM, less potent to PKCδ (20 nM), PKCε (73 nM) and little active to PKCζ (1086 nM). Phase 3. Pan PKCη, IC50: 4 nM