Home Metabolism -DNA Damage/DNA Repair PPAR PPARδ Inhibitors | Agonists | Antagonists

PPARδ Inhibitors | Agonists | Antagonists

  • PPARα
  • PPARβ/δ
  • PPARγ
  • PPARδ
Kat.-Nr. Produktname Informationen Selektiv / Pan IC50 / Ki
S8020 GW0742 GW0742 is a potent and highly selective PPARβ/δ agonist, with IC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ. Pan PPARδ, IC50: 1 nM
S1473 GW501516 GW501516 is a potent and highly selective PPARβ/δ agonist, with EC50 of 1 nM, with 1000-fold selectivity over hPPARα and hPPARγ. Phase 4. Pan PPARδ, EC50: 1.1 nM
S8025 GSK3787 GSK3787 is as a selective and irreversible antagonist of PPARδ with pIC50 of 6.6, with no measurable affinity for hPPARα or hPPARγ. Pan PPARδ, pIC50: 6.6
S2871 T0070907 T0070907 is a potent and selective PPARγ inhibitor with IC50 of 1 nM, with a >800-fold selectivity over PPARα and PPARδ. Pan PPARδ, IC50: 1.8 μM
S2915 GW9662 GW9662 is a selective PPAR antagonist for PPARγ with IC50 of 3.3 nM, with at least 100 to 1000-fold functional selectivity in cells with PPARγ versus PPARα and PPARδ. Pan PPARδ, IC50: 2 μM
S7484 FH535 FH535 is a Wnt/β-catenin signaling inhibitor and also a dual PPARγ and PPARδ antagonist. Pan