SIRT2-selektive Inhibitors | Activators
- SIRT1
- SIRT2
- SIRT3
| Kat.-Nr. | Produktname | Informationen | Selektiv / Pan | IC50 / Ki |
|---|---|---|---|---|
| S7577 | AGK2 | AGK2 is a potent, and selective SIRT2 inhibitor with IC50 of 3.5 μM. | Selective | SIRT2, IC50: 3.5 μM |
| S4900 | Tenovin-6 | Tenovin-6 is a small molecule activator of p53 transcriptional activity. | Pan | SIRT2, IC50: 10 μM |
| S2804 | Sirtinol | Sirtinol is a specific SIRT1 and SIRT2 inhibitor with IC50 of 131 μM and 38 μM, respectively. | Pan | SIRT2, IC50: 38 μM |
| S1396 | Resveratrol | Resveratrol is a phytoalexin produced naturally by several plants with anti-cancer, anti-inflammatory, blood-sugar-lowering and other beneficial cardiovascular effects. | Pan |
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